Optical metrology

Micro & Nanopositioners

Microscopy products

Version française

ASI MS-4400 XYZ Automated Stage


The MS-4400 XYZ provides a high resolution and highly repeatable means of controlling the X, Y, and Z position of the microscope stage. The MS-4400 XY stage has been specifically designed for larger upright microscopes like the Leica DMR-series, the Nikon Eclipse 80i, the Olympus BX series, and the Zeiss Axioplan, Axioskop 2, and Axio Imager. All axes derive their precise control through the use of closed-loop DC servomotors employing high-resolution rotary encoders for positioning feedback. By using closed-loop control of the stage position, there is no chance that the stage will become lost, as can occur with open-loop micro-stepped stages after a number of moves and direction changes. The MS-4400 XY stage utilizes crossed-roller slides, a high-precision lead screw, and zero-backlash miniature geared DC servomotors for smooth and accurate motion. The Z-axis drive also uses ASI's proven line of closed-loop motor drives, each custom fitted to the microscope. The microprocessor-controlled MS-2000 control unit provides for RS 232 and USB communication with a host computer.



  • Closed-loop DC servo control of the X, Y, and Z-axes for precise positioning and highly repeatable focusing
  • Wide dynamic speed range with XY joystick control
  • Utilizes ASI's proven Z-axis drives
  • Z-axis clutch for easy switching between manual and motor-driven focus control
  • Backlit LCD display shows X, Y, and Z coordinates
  • "Zero" and "Home" button for simple stand-alone operations
  • Compact ergonomic tabletop control unit size is 6?D x 9?W x 3?H
  • Microprocessor control with RS-232 serial and USB communications
  • Proven operation with many popular software packages


Specifications for Standard Configuration

XY axis range of travel 100 mm x 100 mm
XY axis resolution (encoder step) 22 nm
XY axis RMS repeatability < 700 nm
XY axis maximum velocity 7 mm/sec
Z axis resolution (encoder step) 50 nm
Z axis repeatability ± 100 nm
Z axis maximum velocity 0.6 mm/sec


MS-4000 Options
  • X, Y, and Z-axis Linear Encoders for high-accuracy positioning and focus control
  • Stage Inserts to hold a variety of slides, dishes, sealed glass chambers, multiwell microplates, perfusers, heaters, and many other special items
  • Auto-Focus for stages with ASI Z-axis drives (requires NTSC, PAL, or S-Video analog signal)
  • Other lead screw pitches are available


Lead Screw Options

Lead Screw Pitch Options Rotary Encoder Resolution Maximum Speed
25.40 mm  (Ultra-coarse) 88 nm 28 mm/sec
12.70 mm  (Super-coarse) 44 nm 14 mm/sec
6.35 mm  (Standard) 22 nm 7 mm/sec
1.57 mm  (Fine) 5.5 nm 1.75 mm/sec
0.635 mm  (Extra-fine) 2.2 nm 0.7 mm/sec
    * Standard Lead Screw Accuracy is 0.25 µm per millimeter

Linear Encoder Options

Axis Resolution Scale Accuracy
XY 10 nm ± 3 Ám per length of scale
Z (12 mm and 25 mm stroke) 50 nm 0.025 Ám per mm


Additional information

MS-4400 automated stage PDF


If you would like more information, please contact us.


Home - Our products - Contact us - General conditions of sale
© Optophase 2006-2015